8/7c - PILOT: Forensic anthropologist Dr. Temperance Brennan teams up with FBI agent Booth to investigate the famous unsolved murder of a young female Senate intern. 9/8c - THE MAN IN THE SUV: Brennan and Booth investigate a case concerning a Middle Eastern diplomat accused of a suicide bombing; further investigation leads them to suspect that the alleged terrorist was actually murdered and framed for the deadly incident.
8/7c - THE GOOD: After a suburban couple is found bludgeoned to death, Detectives Logan (Chris Noth) and Barek (Annabella Sciorra) suspect that their drug-troubled son Kevin (guest star Keith Nobbs) killed his parents' for their cash stash. But when a local investigator pressures the kid into a confession, the city cops discover a conflict of interest. While another suspect with close business ties to the victims emerges, Captain Deakins (Jamey Sheridan) urges Logan and Barek to drop the non-jurisdictional case -- and ponders his own future with the NYPD.
9/8c - TO THE BONE: A rampage of brutal machete slayings that target affluent art owners has Detectives Logan (Chris Noth) and Barek (Annabella Sciorra) looking for some young suspects who were all raised by Chesley (Oscar and Emmy Award-winning guest star Whoopi Goldberg), a strong-willed foster mother. But the case really blows up when Logan unknowingly shoots an undercover cop dead -- and while Captain Deakins (Jamey Sheridan) sticks his neck out for his detective, a shaken Logan must go eye-to-evil-eye with the manipulative Chesley.
8/7c - RUNAWAYS: The team treats an underage and homeless female patient (guest star Bridgit Mendler), but when her symptoms worsen and call for an invasive surgery requiring adult consent, House and Adams argue over whether they should contact social services.
9/8c - NOBODY' FAULT: When a violent incident involving a patient has serious consequences for one staff member, House and the team are placed under review by Dr. Walter Cofield.